body {
    background: #F2F3F5;
}

.loadingpdf {
    position: fixed;
    top: 0px;
    left: 0;
    right: 0;
    bottom: 0;
    background-color: #F2F3F5;
    /*display: flex;*/
    flex-direction: column;
    align-items: center;
    justify-content: center;
    color: #0B1F40;
    z-index: 1000;
    gap: 16px;
    display: none;
}

.loadingleft {
    position: fixed;
    top: 0;
    left: 0;
    width: 35%;
    /*max-width: 516px;*/
    height: 100vh;
    background: rgba(255, 255, 255, 0.7);
    z-index: 1000;
    gap: 16px;
    /*display: flex;*/
    flex-direction: column;
    align-items: center;
    justify-content: center;
    display: none;
}

.loading-spinner {
    width: 48px;
    height: 48px;
    border: 3px solid #D9D9D9;
    border-top: 3px solid #2b7cff;
    border-right: 3px solid #2b7cff;
    border-radius: 50%;
    animation: spin 1s linear infinite;
}

@keyframes spin {
    0% {
        transform: rotate(0deg);
    }

    100% {
        transform: rotate(360deg);
    }
}

.box {
    display: flex;
    height: 100vh;
}

.left-header {
    width: 513px;
    background-color: #0B1F40;
    color: white;
    padding-left: 43px;
    overflow-y: auto;
    position: fixed;
    top: 0px;
    z-index: 9;
    border-bottom: 1px solid #475771;
    height: 61px;
    line-height: 60px;
}

    .left-header img {
        width: 134px;
    }

.left-panel {
    width: 513px;
    background-color: #0B1F40;
    color: white;
    padding: 84px 38px 20px 43px;
    overflow-y: auto;
    position: fixed;
    height: 100vh;
    scrollbar-width: thin;
    scrollbar-color: #475771 #0B1F40;
}

    .left-panel .content-artcle {
        border-bottom: rgba(133, 143, 159, 0.2) 1px solid;
        padding-bottom: 22px;
        margin-bottom: 23px;
    }

        .left-panel .content-artcle label {
            font-size: 12px;
            font-weight: bold;
            color: rgba(255, 255, 255, 0.4);
        }

        .left-panel .content-artcle h1 {
            font-weight: 700;
            font-size: 20px;
            line-height: 23px;
            margin-bottom: 12px;
            margin-top: 8px;
        }

        .left-panel .content-artcle .publish-doi {
            margin-bottom: 8px;
        }

            .left-panel .content-artcle .publish-doi a {
                color: #fff;
                font-size: 12px;
                line-height: 14px;
            }

        .left-panel .content-artcle .viewpage {
            font-weight: 700;
            font-size: 16px;
            line-height: 14px;
            color: #2b7cff;
        }

            .left-panel .content-artcle .viewpage:hover {
                color: #0056b3;
            }

.content-search {
    padding-bottom: 22px;
    border-bottom: rgba(133, 143, 159, 0.2) 1px solid;
    margin-bottom: 20px;
}

    .content-search .label {
        font-size: 12px;
        line-height: 14px;
        color: rgba(255, 255, 255, 0.4);
        padding-bottom: 2px;
    }

    .content-search .search-box {
        margin-top: 5px;
        position: relative;
    }

        .content-search .search-box .search-icon {
            position: absolute;
            right: 10px;
            top: 6px;
        }

        .content-search .search-box .search-out {
            display: inline-block;
        }

        .content-search .search-box .search-hover {
            display: none;
            cursor: pointer;
        }

        .content-search .search-box:hover .search-out {
            display: none;
        }

        .content-search .search-box:hover .search-hover {
            display: inline-block;
            right: 6px;
            top: 5px;
            background: #2B7CFF;
            padding: 6px 6px 6px 7px;
            border-radius: 50%;
        }

    .content-search input {
        background: rgba(255, 255, 255, 0.1);
        border-radius: 24px;
        height: 40px;
        width: 100%;
        padding: 6px 13px 6px 19px;
        border: 1px solid #0B1F40 !important;
        outline: none;
        color: #fff;
        font-size: 14px !important;
    }

        .content-search input[type="text"]::placeholder {
            color: rgba(255, 255, 255, 0.3);
            opacity: 1;
            /* Firefox需要设置不透明度#2b7cff */
        }

        /* 浏览器前缀兼容 */
        .content-search input[type="text"]::-webkit-input-placeholder {
            /* Chrome/Opera/Safari */
            color: rgba(255, 255, 255, 0.3);
        }

        .content-search input[type="text"]::-moz-placeholder {
            /* Firefox 19+ */
            color: rgba(255, 255, 255, 0.3);
            opacity: 1;
        }

        .content-search input[type="text"]:-ms-input-placeholder {
            /* IE 10+ */
            color: rgba(255, 255, 255, 0.3);
        }

        .content-search input[type="text"]:-moz-placeholder {
            /* Firefox 18- */
            color: rgba(255, 255, 255, 0.3);
            opacity: 1;
        }

.content-banner {
    margin-bottom: 24px;
    padding-bottom: 24px;
    border-bottom: rgba(133, 143, 159, 0.2) 1px solid;
}

    .content-banner img {
        width: 100%;
        border-radius: 8px;
    }

.content-alerts {
    background: url(https://cdn.bio-protocol.org/journal/img/pdf-alerts-bg2.svg) center/cover no-repeat;
    border-radius: 8px;
    padding: 20px 22px 22px 24px;
    position: relative;
}

    .content-alerts .emailbottom {
        margin-bottom: 16px;
    }

    .content-alerts .emailbottomAgree {
        margin-bottom: 7px;
    }

    .content-alerts .paddingtop {
        padding-top: 10px;
    }

    .content-alerts .bit_title {
        color: #fff;
        font-weight: 700;
        font-size: 16px;
        line-height: 120%;
    }

    .content-alerts .alert-box {
        margin-bottom: 46px;
    }

        .content-alerts .alert-box .img-left {
            float: left;
            width: 32%;
            position: absolute;
            top: 8px;
            right: 22px;
            max-width:140px;
        }

        .content-alerts .alert-box .alert_body {
            float: left;
            font-size: 12px;
            line-height: 130%;
            color: rgba(255, 255, 255, 0.8);
            width: 56%;
            margin-top: 16px;
            min-height:46px;
        }

            .content-alerts .alert-box .alert_body ul {
                padding-left: 18px;
                margin-top: 8px;
            }

            .content-alerts .alert-box .alert_body li {
                list-style-type: disc;
            }

                .content-alerts .alert-box .alert_body li::marker {
                    font-size: 0.6em; /* 调整点的大小 */
                }

    .content-alerts .el-alerts .el-input__inner {
        border: 1px solid #94A4BF !important;
        height: 44px !important;
        border-radius: 24px !important;
        color: #0B1F40 !important;
        background: rgba(255, 255, 255, 0.1) !important;
    }

    .content-alerts .el-alerts .is-error .el-input__inner {
        border-color: #F56C6C !important;
    }

    .content-alerts .el-alerts .el-checkbox__inner {
        width: 20px;
        height: 20px;
    }

    .content-alerts .el-alerts .el-checkbox__input {
        vertical-align: top;
    }

    .content-alerts .el-alerts .a_subscribe {
        display: inline-block;
        width: 100%;
        border: none;
        background-color: #2b7cff;
        border-radius: 37px;
        text-align: center;
        color: #fff;
        height: 44px;
        line-height: 44px;
        cursor: pointer;
    }

        .content-alerts .el-alerts .a_subscribe img {
            margin-right: 8px;
        }

        .content-alerts .el-alerts .a_subscribe:hover {
            background: #0056b3 !important;
        }

    .content-alerts .el-alerts .el-checkbox__label {
        color: rgba(255, 255, 255, 0.8) !important;
    }

    .content-alerts .el-alerts input[type="text"]::placeholder {
        color: #fff;
        opacity: 1;
        /* Firefox需要设置不透明度#2b7cff */
    }

    /* 浏览器前缀兼容 */
    .content-alerts .el-alerts input[type="text"]::-webkit-input-placeholder {
        /* Chrome/Opera/Safari */
        color: #fff;
    }

    .content-alerts .el-alerts input[type="text"]::-moz-placeholder {
        /* Firefox 19+ */
        color: #fff;
        opacity: 1;
    }

    .content-alerts .el-alerts input[type="text"]:-ms-input-placeholder {
        /* IE 10+ */
        color: #fff;
    }

    .content-alerts .el-alerts input[type="text"]:-moz-placeholder {
        /* Firefox 18- */
        color: #fff;
        opacity: 1;
    }

}

.content-alerts .el-alerts .el-checkbox__inner::after {
    left: 7px;
    top: 3px;
    border-width: 2px;
}

.el-form-item__content {
    word-break: keep-all !important;
}

.content-alerts .el-alerts .ckAgree {
    width: 100%;
    max-width: 640px;
    margin-bottom: 0px;
}

.content-alerts .el-alerts .email-box .el-checkbox__input {
    vertical-align: top;
    height: 44px !important;
    border-radius: 24px !important;
    color: #fff !important;
    width: 100%;
    background: rgba(255, 255, 255, 0.1);
    border: 1px solid #94A4BF;
    padding: 0px 20px;
}

.content-alerts .el-alerts .email-box input[readonly] {
    cursor: text;
}

.content-alerts .el-alerts .email-box .el-checkbox__inner:hover {
    border-color: #2B7CFF !important;
}

.content-alerts .el-alerts .email-box .is-checked .el-checkbox__inner {
    background-color: #2B7CFF !important;
}


.content-alerts .el-alerts .email-box .el-checkbox__label {
    width: 100%;
    color: rgba(255, 255, 255, 0.8);
    word-wrap: break-word;
    white-space: normal;
}

.content-alerts .el-alerts .ckAgree_cn .el-checkbox__input {
    vertical-align: middle;
}


.content-alerts .el-alerts .is-checked .el-checkbox__label {
    color: rgba(255, 255, 255, 0.8);
}

/* WebKit 滚动条样式 */
.left-panel::-webkit-scrollbar {
    width: 3px;
}

.left-panel::-webkit-scrollbar-track {
    background: #0B1F40;
    border-radius: 4px;
}

.left-panel::-webkit-scrollbar-thumb {
    background: #475771;
    border-radius: 4px;
}

    .left-panel::-webkit-scrollbar-thumb:hover {
        background: #475771;
    }

.right-panel {
    flex: 1;
    background-color: #F2F3F5;
    padding: 0;
    margin-left: 513px;
    overflow-y: hidden;
    height: 100vh;
    position: relative;
}

    .right-panel .pdf-tool {
        background: #FFFFFF;
        border-radius: 99px;
        display: inline-block;
        position: absolute;
        top: 80px;
        left: 26px;
        width: 44px;
        text-align: center;
        z-index: 9;
        padding: 10px 0px;
        box-shadow: 0 0 10px rgba(0, 0, 0, 0.2);
    }

        .right-panel .pdf-tool img {
            cursor: pointer;
        }

.btn-download {
    display: none;
}

.email-error {
    color: #F56C6C;
    display: none;
    font-size: 12px;
    margin-top: 4px;
}

.body_subscribe {
    margin-top: 16px;
}

.layui-layer-tips i.layui-layer-TipsT {
    left: -4px !important;
}

.pubmiddle {
    display: inline;
}

.pubmiddleMobile {
    display: none;
}

.agree-box {
    display: none;
    margin-top: 16px;
    overflow: hidden;
}

    .agree-box label {
        cursor: pointer;
    }

    .agree-box input[type='checkbox'] {
        width: 20px;
        height: 20px;
        background-color: #fff;
        -webkit-appearance: none;
        border: 1px solid #e0e0e0;
        border-radius: 2px;
        outline: none;
        cursor: pointer;
        vertical-align: bottom;
        border-color: #aaa;
    }

    .agree-box input[type=checkbox]:checked {
        border: none;
        border-radius: 2px;
        box-shadow: none;
        background: url(data:image/svg+xml;base64,PHN2ZyB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciIHZpZXdCb3g9IjAgMCAyNCAyNCI+CjxwYXRoIGQ9Ik05IDE2LjJMNC44IDEybC0xLjQgMS40TDkgMTkgMjEgN2wtMS40LTEuNEw5IDE2LjJ6IiBmaWxsPSIjZmZmIiBzdHJva2U9IiMjMDI4OEQxIi8+Cjwvc3ZnPg==) no-repeat center;
        background-color: #2b7cff;
    }

#ckagree {
    float: left;
}

.agree-box .cktext {
    float: left;
    display: inline-block;
    width: calc(100% - 24px);
    padding-left: 8px;
    color: rgba(255, 255, 255, 0.8) !important;
}

    .agree-box .cktext a {
        color: #2B7CFF;
    }

.left-panel .bottomfix {
    display: none;
}

.layermsg {
    min-width: 300px;
    max-width: 400px;
    border-radius: 24px;
    position: fixed;
    top: 30px;
    z-index: 9999999;
    padding: 12px 15px 12px 24px;
    font-size: 14px;
    min-height: 48px;
    border: none;
    background-color: #2B7CFF;
    -webkit-transform: translateX(-50%);
    transform: translateX(-50%);
    left: 50%;
    color: #fff;
    display: none;
    -webkit-box-align: center;
    -ms-flex-align: center;
    align-items: center;
    line-height: 19px;
}

    .layermsg p {
        margin: 0px;
        padding: 0px 50px 0 0;
    }

    .layermsg .msgclose {
        position: absolute;
        right: 6px;
        top: 6px;
        border-radius: 50%;
        height: 36px;
        width: 36px;
        padding: 8px;
        display: inline-block;
        background: rgba(255, 255, 255, 0.1);
        cursor: pointer;
        text-align: center;
    }

        .layermsg .msgclose img {
            width: 14px;
        }

.free {
    background: #2b7cff;
    display: inline-block;
    border-radius: 4px;
    padding: 2px 6px 0px 5px;
}

#diviframe {
    position: fixed;
    top: 0;
    right: 0;
    bottom: 0;
    left: 513px;
}
@media (max-width: 768px) {
}